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Harm Reduction In Male Patients Actively Using Anabolic Androgenic Steroids AAS And Performance-Enhancing Drugs PEDs: A Review

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The article \"An Evidence‑Based Guide for the Safe Use of Performance Enhancing Substances\" presents a comprehensive, expert‑driven synthesis of current evidence on commonly used performance‑enhancing agents—including anabolic steroids, growth hormone, erythropoietin, stimulants, and beta‑2 agonists. Using systematic reviews, meta‑analyses, and consensus panels, the authors develop practical recommendations for safe use, emphasizing individualized dosing, monitoring protocols (e.g., hormone levels, cardiovascular metrics), and strategies to mitigate side effects such as androgenic changes, cardiotoxicity, and endocrine disruption. The guide also addresses legal and ethical considerations, providing a framework that balances athletic performance goals with health preservation and regulatory compliance.

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